GenEvolutioN is proud to introduce NanoAmes, a cutting-edge innovation in genotoxicity screening, designed to evaluate the mutagenic potential of chemicals using significantly reduced sample quantities. Presented at [Insert Conference Name], this research highlights how NanoAmes overcomes key challenges in regulatory mutagenicity testing, offering higher sensitivity, reduced resource consumption, and improved accuracy.
Addressing Key Challenges in Mutagenicity Testing
Mutagenicity screening plays a critical role in chemical safety assessment, particularly for pharmaceuticals, cosmetics, and agrochemicals. The standard Ames test (OECD 471) is a widely used bacterial reverse mutation assay, but it requires substantial amounts of test substances, which can be a limiting factor for novel or expensive compounds in early-stage development.
NanoAmes introduces an ultra-miniaturized version of this assay, requiring significantly lower sample volumes while maintaining regulatory compliance and scientific integrity.
Key advantages of NanoAmes
- Ultra-Low Sample Requirement – Reduces the amount of test material needed, making it ideal for early-stage discovery compounds and impurity characterization.
- Enhanced Sensitivity – Maintains accuracy and reproducibility despite the miniaturization, ensuring regulatory acceptance.
- High-Throughput Compatibility – Enables screening of multiple compounds in a 96-well plate format, significantly reducing time and costs.
- Optimized for Small-Scale Testing – A game-changer for pharmaceutical impurities, novel molecules, and nano-sized materials.
Regulatory & scientific relevance
NanoAmes aligns with the current OECD 471 guideline while addressing industry needs for faster, resource-efficient testing methods. By leveraging this innovation, GenEvolutioN empowers companies to comply with international safety regulations while optimizing their research and development strategies.
A new era in genotoxicity testing
By introducing NanoAmes, GenEvolutioN continues to lead in innovation, helping industries ensure the safety of their products with efficient, high-precision toxicology solutions.
The development of NanoAmes also supports the 3Rs principle (Replacement, Reduction, Refinement) by minimizing the need for animal testing and reducing chemical waste, making it an eco-friendly alternative to conventional methods.
